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Bio Design Automation at Technical University of Denmark

D-VASim (Dynamic Virtual Analyzer and simulator) is a tool to analyze and simulate the genetic logic circuit models developed in the Systems Biology Mark-up Language (SBML).These models are usually tested in wet-lab which is a very time consuming and error prone process. Due to the mishandling of the apparatus, experiments are often required to be repeated. In order to avoid this time-consuming in-vitro experiments, these models can be tested through in-silico analysis first. To the best of our knowledge, there exist no in-silico tool which give users an intuitive feeling of performing laboratory experiments virtually.D-VASim give the users an insight of performing laboratory experiments right in the in-silico environment. Similar to the way a user increases an input concentration from the test-tubes into the flask containing bio-model in the laboratory, a user can vary the concentration of input proteins with the help of control knobs and observe its effects on the output concentration graphically in runtime, using D-VASim. D-VASim is the first simulation tool which allow users to interact with the model during runtime.In D-VASim, users can analyze the components of SBML models in a user-friendly manner. A separate virtual instrument can be generated for each SBML model, which serves as a standalone virtual instrument.For more informatiion, please visit https://bda.compute.dtu.dk.